Rebound Science · The evidence collection
Peptide science, metabolic health, performance and longevity — collected in one place.
Guide and article PDFs contain the full reading edition. Study PDFs are citation records; original full text remains with the publisher.
364 results
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Kraus, W.E. 2 years of calorie restriction and cardiometabolic risk (CALERIE): exploratory outcomes of a multicentre, phase 2, randomised controlled trial. The Lancet Diabetes & Endocrinology. 2019.
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Ngandu, T., et al. A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial. The Lancet. 2015.
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Ravussin, E. A 2-Year Randomized Controlled Trial of Human Caloric Restriction: Feasibility and Effects on Predictors of Health Span and Longevity. Journals of Gerontology. 2015.
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Kulkarni, A.S., et al. A Critical Review of the Evidence That Metformin Is a Putative Anti-Aging Drug. Frontiers in Endocrinology. 2021.
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Shaffer F, McCraty R, Zerr CL. A healthy heart is not a metronome: an integrative review of the heart's anatomy and heart rate variability. Front Psychol. 2014.
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Thayer JF et al. A meta-analysis of heart rate variability and neuroimaging studies. Neurosci Biobehav Rev. 2012.
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Ruenzi M, Stolte M, Veljaca M, Oreskovic K, Peterson J, PL 14736 IBD Study Group. A multicenter, randomized, double-blind, placebo-controlled Phase 2 study of PL 14736 enema in patients with mild-to-moderate ulcerative colitis. Gastroenterology. 2005.
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Schultz W, Dayan P, Montague PR. A neural substrate of prediction and reward. Science. 1997.
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Sikiric P. A new gastric juice peptide, BPC. An overview of the stomach-stress-organoprotection hypothesis and beneficial effects of BPC. J Physiol Paris. 1993.
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Kraig E, Linehan LA, Liang H. A randomized control trial to establish the feasibility and safety of rapamycin treatment in an older human cohort. Exp Gerontol. 2018.
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Urfer SR, Kaeberlein TL, Mailheau S, et al. A randomized controlled trial to establish effects of short-term rapamycin treatment in 24 middle-aged companion dogs. GeroScience. 2017.
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Lyoo IK. A randomized, double-blind placebo-controlled trial of oral creatine monohydrate augmentation for enhanced response to a selective serotonin reuptake inhibitor in women with major depressive disorder. Am J Psychiatry. 2012.
Research article · 2026-09-24
Regulatory agencies are tightening oversight on research peptides as gray-market claims blur boundaries. Here is what increased enforcement means for legitimate scientific investigation.
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Epel, E.S., Blackburn, E.H., et al. Accelerated telomere shortening in response to life stress. Proceedings of the National Academy of Sciences (PNAS). 2004.
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Epel, E.S., Blackburn, E.H., Lin, J., Dhabhar, F.S., Adler, N.E., Morrow, J.D., Cawthon, R.M. Accelerated telomere shortening in response to life stress. PNAS. 2004.
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Akintola AA, Noordam R, Jansen SW, de Craen AJ, Ballieux BE, Cobbaert CM, Mooijaart SP, Pijl H, Westendorp RG, van Heemst D. Accuracy of Continuous Glucose Monitoring Measurements in Normo-Glycemic Individuals. PLoS One. 2015.
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Krivic A, Anic T, Seiwerth S, Huljev D, Sikiric P. Achilles detachment in rat and stable gastric pentadecapeptide BPC 157: promoted tendon-to-bone healing and opposed corticosteroid aggravation. J Orthop Res. 2008.
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Holloszy JO, Coyle EF. Adaptations of skeletal muscle to endurance exercise and their metabolic consequences. J Appl Physiol. 1984.
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Gkogkolou, P., Böhm, M. Advanced glycation end products: Key players in skin aging?. Dermato-Endocrinology. 2012.
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Fried, L.P., et al. Aging and the HPA axis: Stress and resilience in older adults. Neuroscience & Biobehavioral Reviews. 2009.
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Fries, J.F. Aging, natural death, and the compression of morbidity. New England Journal of Medicine. 1980.
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Arriola Apelo SI, Neuman JC, Baar EL. Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system. Aging Cell. 2016.
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Jäger S, Handschin C, St-Pierre J, Spiegelman BM. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci U S A. 2007.
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Hu D, Zhang X, et al. An injectable hydroxyapatite microsphere filler loaded with GHK-Cu tripeptide for anti-Inflammatory and antioxidant. Colloids Surf B Biointerfaces. 2025.
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Shaffer F, Ginsberg JP. An Overview of Heart Rate Variability Metrics and Norms. Front Public Health. 2017.
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Ridker, P.M. Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease. New England Journal of Medicine. 2017.
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Sniderman, A.D., et al. Apolipoprotein B Particles and Cardiovascular Disease: A Narrative Review. JAMA Cardiology. 2021.
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Cai, Y., Zimmer, Z., et al. Are We Adding Pain-Free Years to Life? A Test of Compression Versus Expansion of Morbidity. The Journals of Gerontology: Series A. 2024.
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Ogórek K, Nowak K, et al. Are We Ready to Measure Skin Permeation of Modern Antiaging GHK-Cu Tripeptide Encapsulated in Liposomes?. Molecules. 2025.
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San-Millán I, Brooks GA. Assessment of metabolic flexibility by means of measuring blood lactate, fat, and carbohydrate oxidation responses to exercise in professional endurance athletes and less-fit individuals. Sports Med. 2018.
